COVID-19
Compassionate Use of Remdesivir for Patients with Severe Covid-19 DOI: 10.1056/NEJMoa2007016 RemdesivirはウイルスRNAポリメラーゼを阻害するヌクレオチドアナログのプロドラッグでSARS-CoV-2に対してin vitroで活性があることが示されている COVID-19…
Use of Hydroxychloroquine and Chloroquine During the COVID-19 Pandemic: What Every Clinician Should Know Ann Intern Med. 2020 Mar 31. doi: 10.7326/M20-1334. [Epub ahead of print] クロロキンとヒドロキシクロロキンはインフルエンザ、コロナウイ…
Guideline: An international panel provided 54 statements or recommendations for management of ICU patients with COVID-19. Crit Care Med. 2020 Mar 27. doi: 10.1097/CCM.0000000000004363. Surviving Sepsis Campaign COVID-19 panelによるガイドラ…
In adults hospitalized with severe COVID-19 infection, adding lopinavir-ritonavir to standard care did not decrease time to clinical improvement. N Engl J Med. 2020 Mar 18. doi: 10.1056/NEJMoa2001282. lopinavir-ritonavir(カレトラ®:HIV治…
Characteristics and Outcomes of 21 Critically Ill Patients With COVID-19 in Washington State. JAMA. 2020 Mar 19. doi: 10.1001/jama.2020.4326. [Epub ahead of print] JAMAのLetter Evergreen Healthcare, Kirklandからの報告 2020年2月20日から3月5…
Risk Factors Associated With Acute Respiratory Distress Syndrome and Death in Patients With Coronavirus Disease 2019 Pneumonia in Wuhan, China JAMA Intern Med. 2020 Mar 13. doi: 10.1001/jamainternmed.2020.0994. [Epub ahead of print] COVID-…