息づく内科医

関東地方の呼吸器内科医です。

2020-06-01から1ヶ月間の記事一覧

癌性胸膜炎に対する胸膜癒着術でタルクの混濁液のドレーン注入と局麻下胸腔鏡での散布の比較

Thoracoscopy and talc poudrage compared with intercostal drainage and talc slurry infusion to manage malignant pleural effusion: the TAPPS RCT. Health Technol Assess. 2020 Jun;24(26):1-90. doi: 10.3310/hta24260. (Original study) 英国では毎…

NSCLCの免疫療法の治療バイオマーカーとしての循環miRNA、細胞外miRNA含有小胞

Circulating miRNAs and extracellular vesicle containing miRNAs as response biomarkers of anti PD-1/PD-L1 therapy in non-small-cell lung cancer. J Thorac Oncol. 2020 Jun 18. pii: S1556-0864(20)30467-6. doi: 10.1016/j.jtho.2020.05.022. [Epub…

再発性の癌関連静脈血栓症に対する修正Ottawaスコアの診断性能

Predictive ability of modified Ottawa score for recurrence in patients with cancer-associated venous thromboembolism: From the COMMAND VTE Registry. Thromb Res. 2020 Jul;191:66-75. doi: 10.1016/j.thromres.2020.04.047. Epub 2020 May 4. (Ori…

胸水中のSARS-CoV-2のRT-PCRが陽性となった1例

First Detection of SARS-CoV-2 by Real-Time Reverse-Transcriptase-Polymerase-Chain-Reaction (RT-PCR) Assay in Pleural Fluid Chest. 2020 Jun 11;S0012-3692(20)31660-3. COVID-19はSARS-CoV-2による世界中でパンデミックとなった感染症で、無症候性か…

ダイアモンド・プリンセスのCOVID-19の104例

Clinical characteristics of COVID-19 in 104 people with SARS-CoV-2 infection on the Diamond Princess cruise ship: a retrospective analysis Lancet Infectious Disease Published:June 12, 2020DOI:https://doi.org/10.1016/S1473-3099(20)30482-5 …

重症COVID-19に対するConvalescent Plasma(回復期患者からの血清療法)のRCT

Effect of Convalescent Plasma Therapy on Time to Clinical Improvement in Patients With Severe and Life-threatening COVID-19: A Randomized Clinical Trial. JAMA. 2020 Jun 3. pii: 2766943. doi: 10.1001/jama.2020.10044. (Original study) Conval…

ALK陽性肺癌の血栓症のリスク

Impact of ALK Rearrangement on Venous and Arterial Thrombotic Risk in Non-Small Cell Lung Cancer. J Thorac Oncol. 2020 May 10. pii: S1556-0864(20)30380-4. doi: 10.1016/j.jtho.2020.04.033. [Epub ahead of print] NSCLCではKhoranaスコアのよう…

サルコイドーシスの診断ガイドライン ATS

Diagnosis and Detection of Sarcoidosis An Official American Thoracic Society Clinical Practice Guideline Am J Respir Crit Care Med. 2020 Apr 15;201(8):e26-e51. doi: 10.1164/rccm.202002-0251ST. (Evidence-based guideline) リンパ節生検につい…

症状で制限した胸腔穿刺の吸引による合併症

Complications following symptom limited thoracentesis using suction.Eur Respir J. 2020 Jun 4. pii: 1902356. doi: 10.1183/13993003.02356-2019. [Epub ahead of print] 吸引による胸腔穿刺は気胸や再膨張性肺水腫を含む合併症のリスクが増えると言わ…

連花清瘟(漢方薬)によるCOVID-19の効果と安全性

Efficacy and Safety of Lianhuaqingwen Capsules, a repurposed Chinese Herb, in Patients with Coronavirus disease 2019: A multicenter, prospective, randomized controlled trial. Phytomedicine. 2020 May 16:153242. doi: 10.1016/j.phymed.2020.15…

NSCLCに対するアテゾリズマブとプラチナ併用療法による術前化学療法

Neoadjuvant atezolizumab and chemotherapy in patients with resectable non-small-cell lung cancer: an open-label, multicentre, single-arm, phase 2 trial Lancet Oncology 2020 May 7 非小細胞肺癌の約25%は切除可能なstage IB-IIIAで、手術前後の化…

アフリカ系アメリカ人のCOVID-19の剖検のケースシリーズ

Pulmonary and cardiac pathology in African American patients with COVID-19: an autopsy series from New Orleans Lancet Respir Med. 2020 May 27doi: 10.1016/S2213-2600(20)30243-5 [Epub ahead of print] SARS-CoV-2は全米に急速に拡大し、特にアフ…

INSIGHT study

Tepotinib plus gefitinib in patients with EGFR-mutant non-small-cell lung cancer with MET overexpression or MET amplification and acquired resistance to previous EGFR inhibitor (INSIGHT study): an open-label, phase 1b/2, multicentre, rando…

使い捨てマスクの歴史

A history of the medical mask and the rise of throwaway culture.May 22, 2020: Lancet COVID-19のパンデミックで、フェイスマスクの不足は現代医学と公衆衛生の脆弱性の象徴となった。 口や鼻を覆うのは伝統的な衛生方法で、ペストの鳥の嘴のマスクで代…

Osimertinibによる術後補助化学療法

Osimertinib as adjuvant therapy in patients (pts) with stage IB–IIIA EGFR mutation positive (EGFRm) NSCLC after complete tumor resection: ADAURA. DOI: 10.1200/JCO.2020.38.18_suppl.LBA5 Journal of Clinical Oncology 38, no. 18_suppl Osimerti…