Ambulatory Management of Primary Spontaneous Pneumothorax: An Open-Label, Randomised Controlled Trial Lancet. 2020 Jul 4;396(10243):39-49. doi: 10.1016/S0140-6736(20)31043-6. 原発性の自然気胸はもともと元気な若者に起こる。理想的な管理の方法…
Effect of Colchicine vs Standard Care on Cardiac and Inflammatory Biomarkers and Clinical Outcomes in Patients Hospitalized With Coronavirus Disease 2019: The GRECCO-19 Randomized Clinical Trial. JAMA Netw Open. 2020 Jun 1;3(6):e2013136. d…
Thoracoscopy and talc poudrage compared with intercostal drainage and talc slurry infusion to manage malignant pleural effusion: the TAPPS RCT. Health Technol Assess. 2020 Jun;24(26):1-90. doi: 10.3310/hta24260. (Original study) 英国では毎…
Circulating miRNAs and extracellular vesicle containing miRNAs as response biomarkers of anti PD-1/PD-L1 therapy in non-small-cell lung cancer. J Thorac Oncol. 2020 Jun 18. pii: S1556-0864(20)30467-6. doi: 10.1016/j.jtho.2020.05.022. [Epub…
Predictive ability of modified Ottawa score for recurrence in patients with cancer-associated venous thromboembolism: From the COMMAND VTE Registry. Thromb Res. 2020 Jul;191:66-75. doi: 10.1016/j.thromres.2020.04.047. Epub 2020 May 4. (Ori…
First Detection of SARS-CoV-2 by Real-Time Reverse-Transcriptase-Polymerase-Chain-Reaction (RT-PCR) Assay in Pleural Fluid Chest. 2020 Jun 11;S0012-3692(20)31660-3. COVID-19はSARS-CoV-2による世界中でパンデミックとなった感染症で、無症候性か…
Clinical characteristics of COVID-19 in 104 people with SARS-CoV-2 infection on the Diamond Princess cruise ship: a retrospective analysis Lancet Infectious Disease Published:June 12, 2020DOI:https://doi.org/10.1016/S1473-3099(20)30482-5 …
Effect of Convalescent Plasma Therapy on Time to Clinical Improvement in Patients With Severe and Life-threatening COVID-19: A Randomized Clinical Trial. JAMA. 2020 Jun 3. pii: 2766943. doi: 10.1001/jama.2020.10044. (Original study) Conval…
Impact of ALK Rearrangement on Venous and Arterial Thrombotic Risk in Non-Small Cell Lung Cancer. J Thorac Oncol. 2020 May 10. pii: S1556-0864(20)30380-4. doi: 10.1016/j.jtho.2020.04.033. [Epub ahead of print] NSCLCではKhoranaスコアのよう…
Diagnosis and Detection of Sarcoidosis An Official American Thoracic Society Clinical Practice Guideline Am J Respir Crit Care Med. 2020 Apr 15;201(8):e26-e51. doi: 10.1164/rccm.202002-0251ST. (Evidence-based guideline) リンパ節生検につい…
Complications following symptom limited thoracentesis using suction.Eur Respir J. 2020 Jun 4. pii: 1902356. doi: 10.1183/13993003.02356-2019. [Epub ahead of print] 吸引による胸腔穿刺は気胸や再膨張性肺水腫を含む合併症のリスクが増えると言わ…
Efficacy and Safety of Lianhuaqingwen Capsules, a repurposed Chinese Herb, in Patients with Coronavirus disease 2019: A multicenter, prospective, randomized controlled trial. Phytomedicine. 2020 May 16:153242. doi: 10.1016/j.phymed.2020.15…
Neoadjuvant atezolizumab and chemotherapy in patients with resectable non-small-cell lung cancer: an open-label, multicentre, single-arm, phase 2 trial Lancet Oncology 2020 May 7 非小細胞肺癌の約25%は切除可能なstage IB-IIIAで、手術前後の化…
Pulmonary and cardiac pathology in African American patients with COVID-19: an autopsy series from New Orleans Lancet Respir Med. 2020 May 27doi: 10.1016/S2213-2600(20)30243-5 [Epub ahead of print] SARS-CoV-2は全米に急速に拡大し、特にアフ…
Tepotinib plus gefitinib in patients with EGFR-mutant non-small-cell lung cancer with MET overexpression or MET amplification and acquired resistance to previous EGFR inhibitor (INSIGHT study): an open-label, phase 1b/2, multicentre, rando…
A history of the medical mask and the rise of throwaway culture.May 22, 2020: Lancet COVID-19のパンデミックで、フェイスマスクの不足は現代医学と公衆衛生の脆弱性の象徴となった。 口や鼻を覆うのは伝統的な衛生方法で、ペストの鳥の嘴のマスクで代…
Osimertinib as adjuvant therapy in patients (pts) with stage IB–IIIA EGFR mutation positive (EGFRm) NSCLC after complete tumor resection: ADAURA. DOI: 10.1200/JCO.2020.38.18_suppl.LBA5 Journal of Clinical Oncology 38, no. 18_suppl Osimerti…
Tepotinib in Non–Small-Cell Lung Cancer with MET Exon 14 Skipping MutationsN Engl J Med. 2020 May 29. doi: 10.1056/NEJMoa2004407. Online ahead of print. 癌遺伝子のExon14の転写の損失の原因となるスプライシングの部位の変異は非小細胞肺癌の3-4%…
Point-of-Care Diagnostic Tests for Detecting SARS-CoV-2 Antibodies: A Systematic Review and Meta-Analysis of Real-World Data. J Clin Med. 2020 May 18;9(5). pii: jcm9051515. doi: 10.3390/jcm9051515. SARS-CoV-2はCOVID-19で知られる感染力の高…
Remdesivir for the Treatment of Covid-19 — Preliminary ReportN Engl J Med. 2020 May 22. doi: 10.1056/NEJMoa2007764. COVID-19に対していくつかの治療薬が検討されていたが、有効性を示したものはない。 下気道感染症の入院したCOVID-19に対してRemdes…
A study on infectivity of asymptomatic SARS-CoV-2 carriers. Respir Med. 2020 May 13;169:106026. doi: 10.1016/j.rmed.2020.106026. [Epub ahead of print] COVID-19の進行中のアウトブレイクは世界中に広がった。無症候性のSARS-CoV-2のキャリアは感染…
Clinical Characteristics and Outcomes of 421 Patients with COVID-19 Treated in a Mobile Cabin Hospital. Chest. 2020 May 8. pii: S0012-3692(20)31391-X. doi: 10.1016/j.chest.2020.05.515. [Epub ahead of print] 2019年12月、COVID-19は中国、武漢…
Macrolide resistant Mycobacterium avium complex pulmonary disease following clarithromycin and ethambutol combination therapy. Respir Med. 2020 May 15;169:106025. doi: 10.1016/j.rmed.2020.106025. [Epub ahead of print] Mycobacterium avium c…
Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration for PD-L1 Testing In Non-Small Cell Lung Cancer. Chest. 2020 May 16. pii: S0012-3692(20)31410-0. doi: 10.1016/j.chest.2020.04.059. [Epub ahead of print] 癌細胞でのPD-L1の発現…
Hydroxychloroquine in patients with mainly mild to moderate coronavirus disease 2019: open label, randomised controlled trial. BMJ. 2020 May 14;369:m1849. doi: 10.1136/bmj.m1849. 成人のCOVID-19に対するヒドロキシクロロキンを通常の治療と比較…
Programmed Death Ligand 1 Heterogeneity and its Impact on Benefit from Immune Checkpoint Inhibitors in Non-Small-Cell Lung Cancer. J Thorac Oncol. 2020 May 7. pii: S1556-0864(20)30373-7. doi: 10.1016/j.jtho.2020.04.026. [Epub ahead of prin…
D-dimer in patients infected with COVID-19 and suspected pulmonary embolism Respir Med. 2020 May 13 : 106023. COVID-19で肺血栓塞栓症のリスクファクターを分析することが目的である。 後ろ向きの観察研究を行った。COVID-19の重症感染で肺血栓塞栓症…
Safe performance of diagnostic bronchoscopy/EBUS during the SARS‐CoV‐2 pandemic Respirology. 2020 May 13. doi: 10.1111/resp.13843. [Epub ahead of print] 気管支鏡検査はエアロゾルを発生する手技とされるが、COVID-19のパンデミックにより、急を要…
Bronchial Rheoplasty For Treatment of Chronic Bronchitis: 12 Month Results from a Multi-Center Study. Am J Respir Crit Care Med. 2020 May 14. doi: 10.1164/rccm.201908-1546OC. [Epub ahead of print] 慢性気管支炎は粘膜の増生による痰の増加によ…
Continuous Versus Intermittent Infusion of Vancomycin and the Risk of Acute Kidney Injury in Critically Ill Adults: A Systematic Review and Meta-Analysis. Crit Care Med. 2020 Apr 20. doi: 10.1097/CCM.0000000000004326. 超重症患者はルーチン…